原料介紹 

Alcolec® GPC，也被稱為Alpha-GPC或甘油磷酸膽鹼，其純度高達98%，是一種水溶性磷脂，天然存在於體內，通常來源於大豆等植物，用於記憶和認知健康支持。 膽鹼是所有活細胞的重要組成部分，為乙酰膽鹼的生物合成提供了來源，並支持細胞膜的流動性和完整性。

原料功效

乙酰膽鹼（ACh）是一種有機化學物質，在包括人類在內的許多類型的動物的大腦和身體中起神經遞質的作用，神經遞質是由神經細胞釋放以向其他細胞發送信號的化學物質。 乙酰膽鹼是神經系統運動神經元釋放以激活肌肉的神經遞質。 它也用於自主神經系統，既作為交感神經系統的內部傳導器又作為副交感神經系統釋放的最終產物。 在大腦中，乙酰膽鹼在認知功能中起著重要作用，包括覺醒，注意力，記憶力和動機。Alcolec® GPC作為乙酰膽鹼前體，其增強的生物利用度使其能夠輕鬆通過血腦屏障，安全有效地提高血液和腦的膽鹼水平，並為自閉症，認知，生長激素，運動表現和睡眠提供益處：

• 在組織生長和更新，器官活力，生殖和身心整合中起著至關重要的作用

• 對注意力，精神焦點，回憶和認知有顯著的益處

• 可用於治療自閉症的認知和行為障礙

• 抵禦因腦循環不良或阿爾茨海默病引起的記憶衰退

• 改善中風或循環損傷後的腦部恢復

• 恢復生長激素GH的水平，有助於健康老化和積極的生活方式

• 增強運動員的速度和力量等肌肉表現

• 改善睡眠品質

臨床文獻

1. Ann N Y Acad Sci 1994 Jun 30;717:253-69. Alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, Meli M, Panzarasa R Institute of Internal Medicine and Geriatrics, University of Palermo, Italy. α-甘油磷酸膽鹼恢復急性中風或短暫性腦缺血發作患者的認知功能

2. Drugs Aging 1993 Mar-Apr;3(2):159-64. Multicentre study of l-alpha-glyceryl-phosphorylcholine vs ST200 among patients with probable senile dementia of Alzheimer's type. Parnetti L, Abate G, Bartorelli L, Cucinotta D, Cuzzupoli M, Maggioni M,Villardita C, Senin U Institute of Gerontology and Geriatrics, University of Perugia, Italy. α-甘油磷酸膽鹼改善阿爾茨海默型老年癡呆患者的症狀

3. Pharmacol Biochem Behav 1992 Feb;41(2):445-8. Behavioral effects of L-alpha-glycerylphosphorylcholine: influence on cognitive mechanisms in the rat. Drago F, Mauceri F, Nardo L,Valerio C, Lauria N, Rampello L, Guidi G Institute of Pharmacology, University of Catania Medical School, Italy. α-GPC 改善大鼠的學習和記憶能力

4. Pharmacol Biochem Behav 1991 Aug;39(4):835-40. Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine, on scopolamine-induced amnesia and brain acetylcholine. Lopez CM, Govoni S, Battaini F, Bergamaschi S, Longoni A, Giaroni C,Trabucchi M Institute of Pharmacological Sciences, University of Milan, Italy. α-甘油磷酸膽鹼逆轉東莨菪鹼誘導的健忘症

5. Int J Clin Pharmacol Ther Toxicol 1992 Sep;30(9):331-5. A comparative study of free plasma choline levels following intramuscular administration of L-alpha-glycerylphosphorylcholine and citicoline in normal volunteers. Gatti G, Barzaghi N,Acuto G, Abbiati G, Fossati T, Perucca E Department of Internal Medicine and Therapeutics, University of Pavia, Italy. 正常志願者的游離血漿膽鹼水平在肌內註射L-α-甘油磷酸膽鹼後高於胞磷膽鹼CTC

6. NewTrends Clin Neuropharmacol 1991;5:87. Choline alfoscerate in elderly patients with cognitive decline due to dementing illness. Ban TA, et al. 膽鹼三磷酸鹽治療認知能力下降的老年癡呆症患者

7. Geriatria 1992;4:13. Evaluation of effectiveness and tolerability of alpha-GFC (choline alfoscerate) in patients suffering from slight/moderate cognitive decline. Palleschi M, et al. 評估患有輕度/中度認知下降的患者中α-GFC（膽鹼磷酸膽鹼）的有效性和耐受性

8. Mechs Ageing Dev 2001;22:2041. Choline alfoscerate in cognitive decline and in acute cerebrovascular disease: an analysis of published clinical data. Parnetti L,Amenta F, Gallai V. 膽鹼三磷酸鹽在認知衰退和急性腦血管病中的作用：對已發表臨床數據的分析

9. Growth Hormone II: Basic and Clinical Aspects.Springer-Verlag;1994. Effects of an acetylcholine precursor on GH secretion in elderly subjects. In: Bercu, BB,Walker, RF, eds. Ceda GP, et al. 乙酰膽鹼前體對老年人生長激素分泌的影響

10. Clin Ther 2002;25:178. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial. De Jesus Moreno Moreno M. 用乙酰膽鹼前體膽鹼鹽酸鹽治療輕中度阿爾茨海默病癡呆後的認知改善

Alcolec® GPC是American Lecithin Company的註冊商標

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

美國食品藥物管理局並未對此文宣內容中提起的各項說明做出任何評估。本產品不具任何醫療、診斷、治療和預防疾病的效果。